Dynamic study of macrophages polarization in real time : Cell-based impedance application for ECIS Platform
Inflammatory Diseases app
Inflammation is the underlying process of a large number of pathologies ranging from bacterial infection, septic shock, trauma or even cardiometabolic diseases such as atherosclerosis or obesity, among others…
At Acquire Innovation we focus on atherosclerosis by studying the macrophages’ behavior.
Macrophages are one of the leading immune cells that regulate the immune response through their flexibility to the micro-environment.
However the dynamic or real-time study of macrophages is limited by the lack of appropriate technologies.
The ECIS® platform allows to track in real time :
- Monocyte motility and differentiation in response to pro-atherogenic stimuli
- Macrophages polarization in response to pro-atherogenic stimuli
- The endothelium behavior exposed to pro-atherogenic monocytes or macrophages.