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ECIS Application Cancer Cells - Acquire Innovation

Multi-factor monitoring of cancer cells and their metastatic potential : Cell-based impedance application for ECIS platform

Cancer Cells App

Cancer is an uncontrolled proliferation of cells within the body.

Cancer is a complex multifactorial disease requiring to analyze in vitro :

  • cell adhesion;
  • cell morphology;
  • the quality of cell-cell interactions;
  • the quality of cell-substrate interactions;
  • metastatic potential of cancer cells by monitoring cell invasion.

The ECIS®  impedance platform provides the ability to analyze all of these elements (see publication )

Publications

Spencer, Adrianne; Bakera,, Aaron B.

High Throughput Label Free Measurement of Cancer Cell Adhesion Kinetics Under Hemodynamic Flow Journal Article

Sci Rep, 6 (19854), 2016, ISSN: 2045-2322.

Links | BibTeX

K., Wazir U, Sanders AJ, Wazir AM, Ye L, Jiang WG, Ster IC, Sharma AK, Mokbel

Effects of the knockdown of death-associated protein 3 expression on cell adhesion, growth and migration in breast cancer cells. Journal Article

Onco Rep, 33 (5), pp. 2575-82, 2015.

Links | BibTeX

XU, LIXIANG DING,LIN YE, JIANLI; JIANG, WEN G.

Impact of fibroblast activation protein on osteosarcoma cell lines in vitro Journal Article

Oncol Lett., 7 (3), pp. 699–704, 2014.

Links | BibTeX

Merlin,, Neeraj K. Saxena, Dipali Sharma, Xiaokun Ding, Songbai Lin, Fabio Marra,Didier; Anania, Frank A.

Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells. Journal Article

Cancer Res, 67 (6), pp. 2497–2507, 2007, ISSN: 1538-7445.

Links | BibTeX

 ECIS Platform allows to study metastatic cells behavior